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TLR3 antibody [40C1285.6]

Overexpression
Anti-TLR3 antibody [40C1285.6] used in IHC (Paraffin sections) (IHC-P). GTX13915
Anti-TLR3 antibody [40C1285.6] used in IHC (Paraffin sections) (IHC-P). GTX13915
Anti-TLR3 antibody [40C1285.6] used in Western Blot (WB). GTX13915
Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915
Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915
Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915

Cat. No. GTX13915

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 40C1285.6

Isotype

 IgG1

Application

 WB, ICC/IF, IHC-P, FACS, IP

Reactivity

 Human, Mouse, Dog
Package
50 μg ($399)
See all TLR3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 3 μg/ml
ICC/IF 1:20 - 1:1000
IHC-P 1:20 - 1:1000
FACS 2 - 4 μg / 10⁶ cells
IP 2 μg/ 10⁶ cells
Not tested in other applications.

Calculated MW

104 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 0.05% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to amino acids 55-70 (VLNLTHNQLRRLPAAN) of human TLR3.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor 3 , CD283 , IIAE2

Cellular Localization

Endosome membrane

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq]

Database

Research Area

DATA IMAGES

Anti-TLR3 antibody [40C1285.6] used in IHC (Paraffin sections) (IHC-P). GTX13915

GTX13915 IHC-P Image

IHC-P analysis of mouse colon tissue using GTX13915 TLR3 antibody [40C1285.6].
Dilution : 1:500

Anti-TLR3 antibody [40C1285.6] used in IHC (Paraffin sections) (IHC-P). GTX13915

GTX13915 IHC-P Image

IHC-P analysis of mouse intestine tissue using GTX13915 TLR3 antibody [40C1285.6].
Dilution : 1:500

Anti-TLR3 antibody [40C1285.6] used in Western Blot (WB). GTX13915

GTX13915 WB Image

Overexpression

WB analysis of (A) 293 cells, (B) 293 cells overexpressing human TLR3, (C) human intestine, (D) placenta, (E) heart and (F) ovary tissue lysate using GTX13915 TLR3 antibody [40C1285.6].
Dilution : 3 μg/ml

Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915

GTX13915 FACS Image

FACS (Intracellular staining) analysis of human monocyte using GTX13915 TLR3 antibody [40C1285.6].
Red : Primary antibody
Green : isotype control
Shaded histogram : cell only
Dilution : 0.5 μg/10⁶ cells

Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915

GTX13915 FACS Image

FACS (Intracellular staining) analysis of human monocyte using GTX13915 TLR3 antibody [40C1285.6].
Red : Primary antibody
Green : isotype control
Shaded histogram : cell only
Antibody amount : 0.5μg

Anti-TLR3 antibody [40C1285.6] used in Flow cytometry (FACS). GTX13915

GTX13915 FACS Image

FACS analysis of human B cells using GTX13915 TLR3 antibody [40C1285.6].
Red : primary antibody
Green : isotype control
Dilution : 1 μg/1 x 10⁶ cells

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399