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TLR3 antibody

Anti-TLR3 antibody used in Western Blot (WB). GTX31291
Anti-TLR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31291
Anti-TLR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31291

Cat. No. GTX31291

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, ELISA

Reactivity

 Human, Mouse
Package
100 μg ($399)
See all TLR3 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 0.5 μg/mL
ICC/IF 10 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

104 kDa. ( Note )

Positive Control

K-562 Cell Slide(GTX25535) , EL4 Cell Lysate(GTX27183)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TLR3 antibody was raised against a peptide corresponding to 15 amino acids near the amino terminus of human TLR3.The immunogen is located within amino acids 40 - 90 of TLR3.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor 3 , CD283 , IIAE2

Cellular Localization

Endosome membrane

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor is most abundantly expressed in placenta and pancreas, and is restricted to the dendritic subpopulation of the leukocytes. It recognizes dsRNA associated with viral infection, and induces the activation of NF-kappaB and the production of type I interferons. It may thus play a role in host defense against viruses. Use of alternative polyadenylation sites to generate different length transcripts has been noted for this gene. [provided by RefSeq, Jul 200

Database

Research Area

DATA IMAGES

Anti-TLR3 antibody used in Western Blot (WB). GTX31291

GTX31291 WB Image

WB analysis of EL4 cell lysate using GTX31291 TLR3 antibody.
Working concentration : 0.5 μg/ml

Anti-TLR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31291

GTX31291 ICC/IF Image

ICC/IF analysis of K562 cells using GTX31291 TLR3 antibody.
Working concentration : 2 μg/ml

Anti-TLR3 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31291

GTX31291 ICC/IF Image

ICC/IF analysis of K562 cells using GTX31291 TLR3 antibody.
Working concentration : 10 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399