*Optimal dilutions/concentrations should be determined by the researcher.
|1 - 2 μg / 10⁶ cells
|1:10 - 1:500
Not tested in other applications.
This antibody preferentially recognizes TLR4-MD-2 complex than of TLR4 alone.
PBS, 0.05% BSA, 0.05% Sodium Azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
0.50mg/ml(Please refer to the vial label for the specific concentration.)
This antibody was developed by immunizing rats with the Ba/F3 cell line expressing mouse TLR4 and MD-2 (Akashi et al, 2000).
Protein G purified
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Toll-Like Receptor 4,Lps,Ly87,Ran/M1,Rasl2-8,Tlr4
Membrane, Single-pass type I membrane protein
Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.