GeneTex

  • Country / Location Selection

United States (US)

TLR4 antibody

Anti-TLR4 antibody used in Western Blot (WB). GTX13867
Anti-TLR4 antibody used in IHC (Paraffin sections) (IHC-P). GTX13867

Cat. No. GTX13867

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat, Primate
Package
50 μg ($399)
See all TLR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 2 - 5 μg/ml
ICC/IF 2 - 5 μg/ml
IHC-P 5 μg/ml
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

This antibody was developed against a sythetic peptide corresponding to amino acids in a range between 30-80 of mouse TLR4.

Purification

Protein G purified

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll-like receptor 4 , Lps , Ly87 , Ran/M1 , Rasl2-8

Cellular Localization

Cell membrane

Background

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.

Database

Research Area

DATA IMAGES

Anti-TLR4 antibody used in Western Blot (WB). GTX13867

GTX13867 WB Image

WB analysis of (A) partial recombinant mouse TLR4 protein (2 μg/ml) and (B) RAW264.7 and (C) Daudi cell lysate using GTX13867 TLR4 antibody.
Dilution : 5 μg/ml

Anti-TLR4 antibody used in IHC (Paraffin sections) (IHC-P). GTX13867

GTX13867 IHC-P Image

IHC-P analysis of mouse kidney tissue using GTX13867 TLR4 antibody.
Dilution : 5 μg/ml

REFERENCE

Application Reference

Huang SQ et al. World J Gastroenterol 2021; 27 (9) : 815-834 Abdominal paracentesis drainage attenuates intestinal inflammation in rats with severe acute pancreatitis by inhibiting the HMGB1-mediated TLR4 signaling pathway.
Application : WB
Reactivity : Rat
Submit a Reference

REVIEW

There are currently no reviews for TLR4 antibody (GTX13867). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399