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TLR4 antibody

Anti-TLR4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31674

Cat. No. GTX31674

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 IHC-P, ELISA

Reactivity

 Human
Package
100 μg ($399)
See all TLR4 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

96 kDa. ( Note )

Product Note

TLR4 antibody is predicted to not cross-react with other TLR protein family members.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TLR4 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human TLR4.The immunogen is located within the last 50 amino acids of TLR4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor 4 , ARMD10 , CD284 , TLR-4 , TOLL

Cellular Localization

Cell membrane

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

Database

Research Area

DATA IMAGES

Anti-TLR4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31674

GTX31674 IHC-P Image

IHC-P analysis of human placenta tissue using GTX31674 TLR4 antibody.
Working concentration : 5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399