APPLICATION
Application Note
The antibody has been tested by ELISA and Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended dilution range for Western blot analysis is 1:500 ~ 2,000. Recommended starting dilution is 1:1,000.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS pH7.4
Preservative
0.1% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Recombinant human TLR-7 (451-500aa) purified from E. coli
Purification
By protein-G affinity chromatography
Conjugation
Unconjugated
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET
Synonyms
toll like receptor 7 , TLR7-like
Cellular Localization
Endoplasmic reticulum membrane , Endosome , Lysosome
Background
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX53802 WB Image
WB analysis of Ramos lysates (80ug) using TLR-7 antibody at a dilution of 1:1,000.
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REFERENCE
There are currently no references for TLR7 antibody [4F4] (GTX53802). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TLR7 antibody [4F4] (GTX53802). Be the first to share your experience with this product.