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TLR9 antibody [5G5]

Cat. No. GTX76032

Reference 2

Host

 Mouse

Clonality

 Monoclonal

Clone Name

 5G5

Isotype

 IgG2a

Application

 WB, IHC-P, IHC-Fr, FACS

Reactivity

 Human, Mouse, Dog
Package
50 μg ($399)
See all TLR9 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
IHC-P Assay dependent
IHC-Fr Assay dependent
FACS Assay dependent
Not tested in other applications.

Calculated MW

116 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Fusion protein of human TLR9 (amino acids 1-815).

Purification

Purified IgG

Conjugation

Unconjugated

RRID

AB_377178

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

toll like receptor 9 , CD289

Cellular Localization

Endoplasmic reticulum membrane , Endosome , Lysosome

Background

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]

Database

Research Area

REFERENCE

Clone Reference

Batsford S et al. Nephrol Dial Transplant. 2011; 26 (4):1413-6 Protein level expression of Toll-like receptors 2, 4 and 9 in renal disease.
Application : IHC-Fr
Reactivity : Human
Ahmad-Nejad P et al. Eur J Immunol. 2002; 32 (7):1958-68 Bacterial CpG-DNA and lipopolysaccharides activate Toll-like receptors at distinct cellular compartments.
Application : WB, FACS
Reactivity : Mouse
Submit a Reference

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399