GeneTex

  • Country / Location Selection

United States (US)

TMC6 antibody

Anti-TMC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85762
Anti-TMC6 antibody used in Western Blot (WB). GTX85762

Cat. No. GTX85762

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
50 μg ($539)
See all TMC6 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/ml
IHC-P 5 μg/ml
ELISA Assay dependent
Not tested in other applications.

Calculated MW

90 kDa. ( Note )

Product Note

This EVER1 antibody does not cross-react with EVER2.

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A 14 amino acid synthetic peptide near the N-terminus of human EVER1. The immunogen is located within the first 50 amino acids of EVER1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane channel like 6 , EV1 , EVER1 , EVIN1 , LAK4P , TMC6

Cellular Localization

Endoplasmic reticulum membrane

Background

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TMC6 antibody used in IHC (Paraffin sections) (IHC-P). GTX85762

GTX85762 IHC-P Image

IHC-P analysis of human testis tissue using GTX85762 TMC6 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 5 μg/ml

Anti-TMC6 antibody used in Western Blot (WB). GTX85762

GTX85762 WB Image

WB analysis of A-20 cell lysate using GTX85762 TMC6 antibody.
Dilution : 1 μg/mL (Lane A) and 2 μg/mL (Lane B)

REFERENCE

There are currently no references for TMC6 antibody (GTX85762). Be the first to share your publications with this product.
Submit a Reference

REVIEW

There are currently no reviews for TMC6 antibody (GTX85762). Be the first to share your experience with this product.
Submit a Review
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 539