GeneTex
United States (US)

TMC8 antibody

TMC8-antibody-GTX86980-IHC-1_18122102_652.jpg

Cat No. GTX86980

Host Rabbit
Clonality Polyclonal
Application IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

We recommend the following starting dilutions:

IHC: 1:50~1:100
ELISA: 1:5000

Optimal dilutions should be determined experimentally by the end user.

Calculated MW

81 kDa. ( Note )

Specificity/Sensitivity

TMC8 Antibody detects endogenous levels of total TMC8 protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 250% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human TMC8.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transmembrane Channel Like 8,Ev2,Ever2,Evin2,Tmc8

Background

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq]

Database

DATA IMAGES
TMC8-antibody-GTX86980-IHC-1_18122102_652.jpg

GTX86980 IHC-P Image

Immunohistochemistry analysis of paraffin-embedded human tonsil, using TMC8 Antibody. The picture on the right is treated with the synthesized peptide.

Package List Price ($)
$ 339