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TMEM16B antibody

Anti-TMEM16B antibody used in IHC (Paraffin sections) (IHC-P). GTX85241
Anti-TMEM16B antibody used in Western Blot (WB). GTX85241
Anti-TMEM16B antibody used in IHC (Paraffin sections) (IHC-P). GTX85241

Cat. No. GTX85241

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P, ELISA

Reactivity

 Human, Mouse, Rat
Package
100 μg ($399)
See all TMEM16B products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1 - 2 μg/mL
IHC-P 5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

114 kDa. ( Note )

Positive Control

Human Brain Tissue Slide(GTX22203) , Human Small Intestine Tissue Lysate(GTX27923)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TMEM16B antibody was raised against a 19 amino acid synthetic peptide from near the amino terminus of human TMEM16B.The immunogen is located within the first 50 amino acids of TMEM16B.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

anoctamin 2 , C12orf3 , TMEM16B

Cellular Localization

Cell membrane

Background

Calcium-activated chloride channels (CaCC) are present in many cell types and mediate physiological functions such as epithelial secretion, sensory signal transduction, and smooth muscle contraction. Subunits of these CaCC’s include the transmembrane proteins TMEM16A and TMEM16B. TMEM16B is predicted to have eight transmembrane domains with both the amino and carboxy termini in the cytoplasm and is expressed in several tissues including olfactory sensory neurons as well as photoreceptors in mammalian retina. Like TMEM16A, TMEM16B is thought to form at least part of CaCC’s but has different biophysical characteristics such as voltage dependence and unitary conductance.

Database

Research Area

DATA IMAGES

Anti-TMEM16B antibody used in IHC (Paraffin sections) (IHC-P). GTX85241

GTX85241 IHC-P Image

IHC-P analysis of human brain tissue using GTX85241 TMEM16B antibody.
Working concentration : 5 μg/ml

Anti-TMEM16B antibody used in Western Blot (WB). GTX85241

GTX85241 WB Image

WB analysis of human small intestine tissue lysate using GTX85241 TMEM16B antibody.
Working concentration : (A) 1 and (B) 2 μg/ml

Anti-TMEM16B antibody used in IHC (Paraffin sections) (IHC-P). GTX85241

GTX85241 IHC-P Image

IHC-P analysis of human brain tissue using GTX85241 TMEM16B antibody.
Working concentration : 20 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399