GeneTex
United States (US)

TMEM185A antibody

TMEM185A-antibody-GTX87650-ICC_IF-1_18121411_200.jpg
TMEM185A-antibody-GTX87650-WB-1_18121411_205.jpg

Cat No. GTX87650

Host Rabbit
Clonality Polyclonal
Application WB, ICC/IF, ELISA
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

40 kDa. ( Note )

Specificity/Sensitivity

TMEM185A Antibody detects endogenous levels of total TMEM185A protein.
PROPERTIES

Form

Liquid

Buffer

Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized peptide derived from human TMEM185A.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Protein FAM11A

Background

The protein encoded by this gene is predicted to be a transmembrane protein, but this has not been experimentally determined. This gene is better known for localizing to the CpG island of the fragile site FRAXF. The 5-prime untranslated region of this gene contains a CGG trinucleotide repeat sequence that normally consists of 7-40 tandem CGG repeats but which can expand to greater than 300 repeats. Methylation of the CpG island leads to transcriptional silencing of this gene, but neither the silencing nor an expanded repeat region appear to manifest itself in a clear phenotypic manner. Two transcript variants encoding different isoforms have been found for this gene.
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Database

Research Area

DATA IMAGES
TMEM185A-antibody-GTX87650-ICC_IF-1_18121411_200.jpg

GTX87650 ICC/IF Image

Immunofluorescence analysis of MCF7 cells, using TMEM185A Antibody. The picture on the right is treated with the synthesized peptide.

TMEM185A-antibody-GTX87650-WB-1_18121411_205.jpg

GTX87650 WB Image

Western blot analysis of extracts from K562 cells, using TMEM185A Antibody. The lane on the right is treated with the synthesized peptide.