APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| Assay dependent |
| 3 μg/ml |
| Assay dependent |
Not tested in other applications.
Calculated MW
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
A 19 amino acid synthetic peptide near the C-terminus of human TMP21. The immunogen is located within amino acids 160 - 210 of TMP21.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
transmembrane p24 trafficking protein 10 , P24(DELTA) , S31I125 , S31III125 , TMED10 , TMP21 , Tmp21I , p23 , p24d1
Cellular Localization
Golgi apparatus,Cis-Golgi network membrane,Melanosome,Endoplasmic reticulum membrane,Endoplasmic reticulum-Golgi intermediate compartment membrane,Cytoplasmic vesicle,Secretory vesicle membrane,Cell membrane,Trans-Golgi network membrane
Background
This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX85770 WB Image
WB analysis of Raji cell lysate using GTX85770 TMP21 antibody.
Dilution : 0.5 μg/mL (Lane A), 1 μg/mL (Lane B), and 2 μg/mL (Lane C)
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GTX85770 IHC-P Image
IHC-P analysis of human brain tissue using GTX85770 TMP21 antibody.
Dilution : 20 μg/ml
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GTX85770 IHC-P Image
IHC-P analysis of human prostate tissue using GTX85770 TMP21 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 3 μg/ml
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GTX85770 IHC-P Image
IHC-P analysis of human breast tissue using GTX85770 TMP21 antibody.
Antigen retrieval : Heat-induced antigen retrieval
Dilution : 3 μg/ml
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REFERENCE
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REVIEW
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