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TMPRSS2 antibody, Internal

Anti-TMPRSS2 antibody, Internal used in Western Blot (WB). GTX81494
Anti-TMPRSS2 antibody, Internal used in Flow cytometry (FACS). GTX81494

Cat. No. GTX81494

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, FACS

Reactivity

 Human
Package
400 μl ($399)
See all TMPRSS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:1000
ICC/IF Assay dependent
FACS 1:10-1:50
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic peptide between 314-343 amino acids from the Central region of human TMPRSS2.

Purification

Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane serine protease 2 , PP9284 , PRSS10

Cellular Localization

Cell membrane

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES

Anti-TMPRSS2 antibody, Internal used in Western Blot (WB). GTX81494

GTX81494 WB Image

WB analysis of HepG2 cell lysate (35ug/lane) using GTX81494 TMPRSS2 antibody, Internal.

Anti-TMPRSS2 antibody, Internal used in Flow cytometry (FACS). GTX81494

GTX81494 FACS Image

FACS analysis of HepG2 cells using GTX81494 TMPRSS2 antibody, Internal.
Green : primary antibody
Blue : negative control

REFERENCE

Application Reference

Hoai-Nga Thi Nguyen et al. Front Oncol 2022; 12 : 923467 SARS-CoV-2 M Protein Facilitates Malignant Transformation of Breast Cancer Cells.
Application : FACS
Reactivity : Human
Khanh VC et al. Stem Cells Dev 2021; 30 (15) : 758-772 Wharton's Jelly Mesenchymal Stem Cell-Derived Extracellular Vesicles Reduce SARS-CoV2-Induced Inflammatory Cytokines Under High Glucose and Uremic Toxin Conditions.
Application : ICC/IF
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399