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TMPRSS2 antibody

Overexpression
Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544
Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544
Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544
Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544
Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544
Anti-TMPRSS2 antibody used in Western Blot (WB). GTX64544
Anti-TMPRSS2 antibody used in Western Blot (WB). GTX64544
Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544
Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544

Cat. No. GTX64544

Reference 2

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TMPRSS2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

54 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 140-400 of human TMPRSS2 (NP_001128571.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transmembrane serine protease 2 , PP9284 , PRSS10

Cellular Localization

Cell membrane

Background

This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]

Database

Research Area

DATA IMAGES

Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544

GTX64544 ICC/IF Image

ICC/IF analysis of C6 cells using GTX64544 TMPRSS2 antibody.
Blue : DAPI
Dilution : 1:50

Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544

GTX64544 ICC/IF Image

ICC/IF analysis of U2OS cells using GTX64544 TMPRSS2 antibody.
Blue : DAPI
Dilution : 1:50

Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544

GTX64544 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX64544 TMPRSS2 antibody.
Dilution : 1:50

Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544

GTX64544 ICC/IF Image

ICC/IF analysis of NIH/3T3 cells using GTX64544 TMPRSS2 antibody.
Blue : DAPI
Dilution : 1:50

Anti-TMPRSS2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX64544

GTX64544 ICC/IF Image

ICC/IF analysis of A549 cells using GTX64544 TMPRSS2 antibody.
Blue : DAPI
Dilution : 1:50

Anti-TMPRSS2 antibody used in Western Blot (WB). GTX64544

GTX64544 WB Image

WB analysis of various sample lysates using GTX64544 TMPRSS2 antibody.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TMPRSS2 antibody used in Western Blot (WB). GTX64544

GTX64544 WB Image

WB analysis of various sample lysates using GTX64544 TMPRSS2 antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:500
Loading : 25μg per lane

Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544

GTX64544 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX64544 TMPRSS2 antibody.
Dilution : 1:50

Anti-TMPRSS2 antibody used in IHC (Paraffin sections) (IHC-P). GTX64544

GTX64544 IHC-P Image

IHC-P analysis of human placenta tissue using GTX64544 TMPRSS2 antibody.
Dilution : 1:50

REFERENCE

Application Reference

Lee CY et al. Viruses 2023; 15 (3) Repurposing Astragalus Polysaccharide PG2 for Inhibiting ACE2 and SARS-CoV-2 Spike Syncytial Formation and Anti-Inflammatory Effects.
Application : WB
Li Y et al. Antiviral Res 2023; : 105606 Omicsynin B4 potently blocks coronavirus infection by inhibiting host proteases cathepsin L and TMPRSS2.
Application : WB
Reactivity : Human
Submit a Reference

REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399