APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1-3μg/ml |
| 2-4μg/ml |
|
Note :
IHC-P
Human Liver shows staining of sinusoidal lining cells.
|
Not tested in other applications.
Calculated MW
Positive Control
The peptide used to generate this antibody is available for purchase (GTX22236-PEP).
Product Note
This antibody is expected to recognise both reported isoforms (NP_037390.2 and NP_660183.1).
PROPERTIES
Form
Liquid
Buffer
TBS, 0.5% BSA
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
Peptide with sequence C-RESQSYLVEDLERS, from the C Terminus of the protein sequence according to NP_037390.2; NP_660183.1.
Purification
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
PYD and CARD domain containing , ASC , CARD5 , TMS , TMS-1 , TMS1
Cellular Localization
Cytoplasm , Endoplasmic reticulum , Mitochondrion , Nucleus
Background
This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Database
Research Area
DATA IMAGES
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GTX22236 IHC-P Image
IHC-P analysis of human tonsil using GTX22236 TMS1 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5μg/ml
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GTX22236 IHC-P Image
IHC-P analysis of human liver using GTX22236 TMS1 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 2.5μg/ml
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GTX22236 WB Image
WB analysis of U937 lysate using GTX22236 TMS1 antibody, C-term.
Dilution : 2μg/ml
Loading : 35μg protein in RIPA buffer
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REFERENCE
There are currently no references for TMS1 antibody, C-term (GTX22236). Be the first to share your publications with this product.
REVIEW
There are currently no reviews for TMS1 antibody, C-term (GTX22236). Be the first to share your experience with this product.
