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TNF Receptor I antibody [H398]

Cat No. GTX74902

Host

Mouse

Clonality

Monoclonal

Clone Name

H398

Isotype

IgG2a

Application

FACS, ELISA, RIA

Reactivity

Human, Rabbit
Package
100 μg ($319)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
FACS Assay dependent
ELISA Assay dependent
RIA Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

Specificity/Sensitivity

This antibody recognizes an extracellular domain of TNF Receptor I.

PROPERTIES

Form

Liquid

Buffer

PBS, 0.09% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Purified human tumour necrosis factor receptor type 1.

Purification

Protein A purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Tnf Receptor Superfamily Member 1A , Cd120A , Fpf , Tbp1 , Tnf-R , Tnf-R-I , Tnf-R55 , Tnfar , Tnfr1 , Tnfr55 , Tnfr60 , P55 , P55-R , P60 , Tnfrsf1A

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is one of the major receptors for the tumor necrosis factor-alpha. This receptor can activate NF-kappaB, mediate apoptosis, and function as a regulator of inflammation. Antiapoptotic protein BCL2-associated athanogene 4 (BAG4/SODD) and adaptor proteins TRADD and TRAF2 have been shown to interact with this receptor, and thus play regulatory roles in the signal transduction mediated by the receptor. Germline mutations of the extracellular domains of this receptor were found to be associated with the autosomal dominant periodic fever syndrome. The impaired receptor clearance is thought to be a mechanism of the disease. [provided by RefSeq, Jul 2008]

Database

Research Area

REFERENCE

There are currently no references for TNF Receptor I antibody [H398] (GTX74902). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TNF Receptor I antibody [H398] (GTX74902). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 319