FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.
Recognizes an extracellular region of mouse TNF Receptor I (also known as TNFR1, p55)
0.1% Sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.
0.10 mg/ml (Please refer to the vial label for the specific concentration.)
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
tumor necrosis factor receptor superfamily, member 1a , CD120a , FPF , TNF-R , TNF-R-I , TNF-R1 , TNF-R55 , TNF-alphaR1 , TNFAR , TNFR60 , TNFRI , TNFRp55 , TNFalpha-R1 , Tnfr-2 , Tnfr1 , p55 , p55-R
Cell membrane; Single-pass type I membrane protein , Golgi apparatus membrane
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]