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TNF Receptor I antibody [HM104] (PE)

Cat No. GTX16198

Host

Rat

Clonality

Monoclonal

Clone Name

HM104

Isotype

IgG2a

Application

ICC/IF, FACS

Reactivity

Mouse
Package
500 μl ($359)

APPLICATION

Application Note

FACS: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the researcher.

Calculated MW

50 kDa. ( Note )

Product Note

Recognizes an extracellular region of mouse TNF Receptor I (also known as TNFR1, p55)

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline containing 0.1% sodium azide and BSA

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE. Protect from light.

Concentration

0.10 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Purification

Purified IgG

Conjugation

Phycoerythrin (PE)

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tumor necrosis factor receptor superfamily, member 1a , CD120a , FPF , TNF-R , TNF-R-I , TNF-R1 , TNF-R55 , TNF-alphaR1 , TNFAR , TNFR60 , TNFRI , TNFRp55 , TNFalpha-R1 , Tnfr-2 , Tnfr1 , p55 , p55-R

Cellular Localization

Cell membrane; Single-pass type I membrane protein , Golgi apparatus membrane

Background

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]

Database

Research Area

REFERENCE

REVIEW

TNF Receptor I antibody [HM104] (PE) Cat No. GTX16198

Rating ( Average 5 based on 2 users reviews)
Application
Immunocytochemistry/ Immunofluorescence(ICC/IF) ( Average 5 based on 1 users reviews)
Flow cytometry(FACS) ( Average 5 based on 1 users reviews)
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : ICC/IF
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Front Immunol in 2019.PMID: 31921183
Date : Anonymous submitted on 18-Mar-2021
Score :
Application Tested : FACS
Sample Species : Ms
Figure Note : The data was peer reviewed and published in the journal Front Immunol in 2019.PMID: 31921183
SDS
Sodium Azide.pdf