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TNF Receptor I antibody

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX02170
Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX02170
Anti-TNF Receptor I antibody used in Western Blot (WB). GTX02170

Cat. No. GTX02170

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human
Package
100 μl ($399)
See all TNF Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P 1:500-1:2000
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

Filter-sterilized PBS

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant Human TNF Receptor I protein (GTX01370-pro)

Purification

Purified by Protein A and Antigen Affinity

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 1A , CD120a , FPF , TBP1 , TNF-R , TNF-R-I , TNF-R55 , TNFAR , TNFR1 , TNFR55 , TNFR60 , p55 , p55-R , p60

Cellular Localization

Cell membrane , Golgi apparatus membrane , Secreted

Background

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX02170

GTX02170 IHC-P Image

IHC-P analysis of human brain tissue section using GTX02170 TNF Receptor I antibody.
Dilution : 1:1000

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX02170

GTX02170 IHC-P Image

IHC-P analysis of human placenta tissue section using GTX02170 TNF Receptor I antibody.
Dilution : 1:1000

Anti-TNF Receptor I antibody used in Western Blot (WB). GTX02170

GTX02170 WB Image

WB analysis of various samples using GTX02170 TNF Receptor I antibody.
Lane A : HepG2 whole cell lysate
Lane B : 293T whole cell lysate
Lane C : THP-1 whole cell lysate
Dilution : 1:500
Loading : 30 μg

REFERENCE

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REVIEW

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Package List Price ($)
$ 399