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TNF Receptor I antibody

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550
Anti-TNF Receptor I antibody used in Western Blot (WB). GTX33550
Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550
Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550
Anti-TNF Receptor I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33550

Cat. No. GTX33550

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TNF Receptor I products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 22-211 of human TNFRSF1A (NP_001056.1).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TNF receptor superfamily member 1A , CD120a , FPF , TBP1 , TNF-R , TNF-R-I , TNF-R55 , TNFAR , TNFR1 , TNFR55 , TNFR60 , p55 , p55-R , p60

Cellular Localization

Cell membrane,Golgi apparatus membrane,Secreted

Background

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550

GTX33550 IHC-P Image

IHC-P analysis of rat spleen tissue using GTX33550 TNF Receptor I antibody.
Dilution : 1:100

Anti-TNF Receptor I antibody used in Western Blot (WB). GTX33550

GTX33550 WB Image

WB analysis of various sample lysates using GTX33550 TNF Receptor I antibody. The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550

GTX33550 IHC-P Image

IHC-P analysis of rat lung tissue using GTX33550 TNF Receptor I antibody.
Dilution : 1:100

Anti-TNF Receptor I antibody used in IHC (Paraffin sections) (IHC-P). GTX33550

GTX33550 IHC-P Image

IHC-P analysis of mouse spleen tissue using GTX33550 TNF Receptor I antibody.
Dilution : 1:100

Anti-TNF Receptor I antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX33550

GTX33550 ICC/IF Image

ICC/IF analysis of BALB-3T3 cells using GTX33550 TNF Receptor I antibody.
Blue : DAPI
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399