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TNF Receptor I antibody

Anti-TNF Receptor I antibody used in Western Blot (WB). GTX59625

Cat No. GTX59625

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC

Reactivity

Human, Mouse, Rat, Rabbit, Bovine, Hamster, Monkey
Package
100 μg ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-4 μg/ml
IHC 10-20 μg/ml
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.2, 30% glycerol, 0.5% BSA, 0.01% thimerosal

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide surrounding amino acid 32 of human TNF-RI

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

tumor necrosis factor receptor superfamily, member 1a , CD120a , FPF , TNF-R , TNF-R-I , TNF-R1 , TNF-R55 , TNF-alphaR1 , TNFAR , TNFR60 , TNFRI , TNFRp55 , TNFalpha-R1 , Tnfr-2 , Tnfr1 , p55 , p55-R

Cellular Localization

Cell membrane; Single-pass type I membrane protein,Golgi apparatus membrane

Background

This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mice lacking a functional copy of this gene exhibit impaired immune function. [provided by RefSeq, Sep 2016]

Database

Research Area

DATA IMAGES

Anti-TNF Receptor I antibody used in Western Blot (WB). GTX59625

GTX59625 WB Image

WB analysis of rat brain tissue lysate using GTX59625 TNF Receptor I antibody.

REFERENCE

There are currently no references for TNF Receptor I antibody (GTX59625). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TNF Receptor I antibody (GTX59625). Be the first to share your experience with this product.
SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf