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TNF Receptor II antibody

Anti-TNF Receptor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31250
Anti-TNF Receptor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31250

Cat No. GTX31250

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, ELISA, Functional Assay
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.2μg/ml
ICC/IF 3μg/ml
ELISA 0.5-2μg/ml
Functional Assay 15-20μg/ml
Not tested in other applications.

Calculated MW

48 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant human TNF Receptor II.

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Receptor Superfamily Member 1B,Cd120B,Tbpii,Tnf-R-Ii,Tnf-R75,Tnfbr,Tnfr1B,Tnfr2,Tnfr80,P75,P75Tnfr,Tnfrsf1B

Background

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES
Anti-TNF Receptor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31250

GTX31250 ICC/IF Image

ICC/IF analysis of PC3 cells using GTX31250 TNF receptor II antibody(green). Counterstained with actin, red and nuclei, blue

Anti-TNF Receptor II antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX31250

GTX31250 ICC/IF Image

ICC/IF analysis of Caco-2 cells using GTX31250 TNF receptor II antibody(green). Counterstained with actin, red and nuclei, blue

SDS
PBS.pdf
Package List Price ($)
$ 319