GeneTex
United States (US)

TNF alpha antibody [195]

Cat No. GTX38915

Host Mouse
Clonality Monoclonal
Clone Name 195
Isotype IgG3
Application IHC-Fr, Functional Assay, IB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-Fr Assay dependent
Functional Assay Assay dependent
IB Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.0mg/ml

Antigen Species

Human

Immunogen

Recombinant human tumour necrosis factor alpha produced in Escherichia coli.

Purification

Purified IgG

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

TNFSF2 Antibody , tumor necrosis factor Antibody , DIF Antibody , TNF-alpha Antibody , TNFA Antibody , TNF Antibody

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq, Jul 2008]
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Database

Research Area

SDS
PBS.pdf