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TNF alpha antibody [XT3.11]

Anti-TNF alpha antibody [XT3.11] used in Western Blot (WB). GTX14195

Cat. No. GTX14195

Host

 Rat

Clonality

 Monoclonal

Clone Name

 XT3.11

Isotype

 IgG1

Application

 WB, Neutralizing/Inhibition

Reactivity

 Mouse
Package
500 μg ($399)
See all TNF alpha products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB Assay dependent
Neutralizing/Inhibition Assay dependent
Not tested in other applications.

Calculated MW

26 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.2μm-filtered PBS (pH8)

Preservative

No preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC. DO NOT FREEZE.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Mouse

Immunogen

Recombinant mouse TNFα

Purification

Protein G purified
From tissue culture supernatant

Purity

>95% (Determined by SDS-PAGE)

Endotoxin

< 0.002 EU/弮g (Determined by LAL assay)

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Cellular Localization

Cell membrane,Membrane,Secreted

Background

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. Members of this family are classified based on primary sequence, function, and structure. This protein is synthesized as a type-II transmembrane protein and is reported to be cleaved into products that exert distinct biological functions. It plays an important role in the innate immune response as well as regulating homeostasis but is also implicated in diseases of chronic inflammation. In mouse deficiency of this gene is associated with defects in response to bacterial infection, with defects in forming organized follicular dendritic cell networks and germinal centers, and with a lack of primary B cell follicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Database

Research Area

DATA IMAGES

Anti-TNF alpha antibody [XT3.11] used in Western Blot (WB). GTX14195

GTX14195 WB Image

WB analysis of purified TNF alpha recombinant protein using GTX14195 TNF alpha antibody [XT3.11].
Lane 1 : 1 ug reduced purified mouse TNFα
Lane 2 : 0.5 ug reduced purified mouseTNFα
Dilution : 15 ug/ml

REFERENCE

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REVIEW

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Package List Price ($)
$ 399