GeneTex
  • Country / Location Selection

United States (US)

TNNI1 antibody, N-term

Anti-TNNI1 antibody, N-term used in Western Blot (WB). GTX47077
Anti-TNNI1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47077
Anti-TNNI1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47077

Cat No. GTX47077

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μl ($359)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.2-2.5 ug/ml
IHC-P 2-10 ug/ml
Not tested in other applications.

Calculated MW

22 kDa. ( Note )

Positive Control

HepG2

PROPERTIES

Form

Liquid

Buffer

1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5-1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a N-terminal region of Human TNNI1

Purification

Affinity Purified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

troponin I1, slow skeletal type , SSTNI , TNN1

Background

Troponin proteins associate with tropomyosin and regulate the calcium sensitivity of the myofibril contractile apparatus of striated muscles. Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. The TnI-fast and TnI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TnI-cardiac gene is expressed exclusively in cardiac muscle tissue. This gene encodes the Troponin-I-skeletal-slow-twitch protein. This gene is expressed in cardiac and skeletal muscle during early development but is restricted to slow-twitch skeletal muscle fibers in adults. The encoded protein prevents muscle contraction by inhibiting calcium-mediated conformational changes in actin-myosin complexes. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TNNI1 antibody, N-term used in Western Blot (WB). GTX47077

GTX47077 WB Image

WB analysis of HepG2 cells using GTX47077 TNNI1 antibody at 0.2-1μg/ml.

Anti-TNNI1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47077

GTX47077 IHC-P Image

IHC-P analysis of human skeletal muscle tissue using GTX47077 TNNI1 antibody at 5μg/ml.

Anti-TNNI1 antibody, N-term used in IHC (Paraffin sections) (IHC-P). GTX47077

GTX47077 IHC-P Image

IHC-P analysis of human kidney tissue using GTX47077 TNNI1 antibody at 4.0-8.0μg/ml.

REFERENCE

There are currently no references for TNNI1 antibody, N-term (GTX47077). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TNNI1 antibody, N-term (GTX47077). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 359