GeneTex
United States (US)

TOP3B antibody

Anti-TOP3B antibody used in Western Blot (WB). GTX34277

Cat No. GTX34277

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
Not tested in other applications.

Calculated MW

97 kDa. ( Note )

Specificity/Sensitivity

Topo IIIβ-1 Polyclonal Antibody detects endogenous levels of Topo IIIβ-1 protein.
PROPERTIES

Form

Liquid

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Synthesized peptide derived from the N-terminal region of human Topo IIIβ-1 at AA range: 30-110.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dna Topoisomerase Iii Beta,Top3B1,Top3B

Background

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
Anti-TOP3B antibody used in Western Blot (WB). GTX34277

GTX34277 WB Image

Western Blot (WB) analysis of specific cells using Topo IIIbeta-1 Polyclonal Antibody.

Package List Price ($)
$ 319