GeneTex
United States (US)

TOPBP1 antibody [C1C2], Internal

GTX104978_40513_20150508_WB_19011506_172.jpg

Cat No. GTX104978

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
Not tested in other applications.

Calculated MW

171 kDa. ( Note )

Positive Control

H1299 , HCT116

Predict Reactivity

Bovine, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1.01mg/ml(Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant protein encompassing a sequence within the center region of human TOPBP1. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

TOP2BP1 antibody, TOPBP1 antibody, DNA topoisomerase II-beta-binding protein 1 antibody, DNA topoisomerase II-binding protein 1 antibody, DNA topoisomerase 2-binding protein 1 antibody, topoisomerase (DNA) II binding protein 1 antibody

Background

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq]

Database

DATA IMAGES
GTX104978_40513_20150508_WB_19011506_172.jpg

GTX104978 WB Image

TOPBP1 antibody detects TOPBP1 protein by western blot analysis. Various whole cell extracts (30 μg) were separated by 5% SDS-PAGE, and the membrane was blotted with TOPBP1 antibody (GTX104978) diluted at a dilution of 1:500.

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169