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TOPBP1 antibody

Anti-TOPBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04859
Anti-TOPBP1 antibody used in Western Blot (WB). GTX04859
Anti-TOPBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04859

Cat. No. GTX04859

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TOPBP1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:2000
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

171 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TOPBP1 (NP_008958.2)._x000D_

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TOP2BP1,TOPBP1,topoisomerase (DNA) II binding protein 1,DNA topoisomerase II binding protein 1

Cellular Localization

Nucleus,Cytoplasm,Cytoskeleton,Microtubule organizing center,Centrosome,Spindle pole,Chromosome

Background

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TOPBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04859

GTX04859 IHC-P Image

IHC-P analysis of rat lung tissue using GTX04859 TOPBP1 antibody.
Antigen retrieval : Microwave antigen retrieval with 10 mM PBS buffer pH 7.2
Dilution : 1:100

Anti-TOPBP1 antibody used in Western Blot (WB). GTX04859

GTX04859 WB Image

WB analysis of various samples using GTX04859 TOPBP1 antibody.
Loading : 25 μg
Dilution : 1:1000

Anti-TOPBP1 antibody used in IHC (Paraffin sections) (IHC-P). GTX04859

GTX04859 IHC-P Image

IHC-P analysis of mouse lung tissue using GTX04859 TOPBP1 antibody.
Antigen retrieval : Microwave antigen retrieval with 10 mM PBS buffer pH 7.2
Dilution : 1:100

REFERENCE

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REVIEW

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Package List Price ($)
$ 399