GeneTex
United States (US)

TOPBP1 antibody

GTX16438_20180530_IHC-P_18121410_430.jpg
GTX16438_20180530_IHC-P_3_18121410_261.jpg
GTX16438_20180530_ICCIF_18121410_693.jpg
GTX16438_20180530_IHC-P_2_18121410_194.jpg
GTX16438_20180530_IHC-P_1_18121410_741.jpg
GTX16438_20180530_WB_18121410_902.jpg

Cat No. GTX16438

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500 - 1:2000
ICC/IF 1:50 - 1:200
IHC-P 1:50 - 1:200
Not tested in other applications.

Calculated MW

171 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1253-1522 of human TOPBP1 (NP_008958.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Dna Topoisomerase Ii Binding Protein 1,Top2Bp1,Topbp1

Background

This gene encodes a binding protein which interacts with the C-terminal region of topoisomerase II beta. This interaction suggests a supportive role for this protein in the catalytic reactions of topoisomerase II beta through transient breakages of DNA strands. [provided by RefSeq, Jul 2008]

Database

DATA IMAGES
GTX16438_20180530_IHC-P_18121410_430.jpg

GTX16438 IHC-P Image

IHC-P analysis of human breast cancer tissue using GTX16438 TOPBP1 antibody.
Dilution : 1:100

GTX16438_20180530_IHC-P_3_18121410_261.jpg

GTX16438 IHC-P Image

IHC-P analysis of mouse heart tissue using GTX16438 TOPBP1 antibody.
Dilution : 1:100

GTX16438_20180530_ICCIF_18121410_693.jpg

GTX16438 ICC/IF Image

ICC/IF analysis of A549 cell using GTX16438 TOPBP1 antibody.
Blue : DAPI

GTX16438_20180530_IHC-P_2_18121410_194.jpg

GTX16438 IHC-P Image

IHC-P analysis of human gastric cancer tissue using GTX16438 TOPBP1 antibody.
Dilution : 1:100

GTX16438_20180530_IHC-P_1_18121410_741.jpg

GTX16438 IHC-P Image

IHC-P analysis of human colon carcinoma tissue using GTX16438 TOPBP1 antibody.
Dilution : 1:100

GTX16438_20180530_WB_18121410_902.jpg

GTX16438 WB Image

WB analysis of 293T cell lysate using GTX16438 TOPBP1 antibody.The signal was developed with ECL plus-Enhanced.
Dilution : 1:1000
Loading : 25μg per lane

Package List Price ($)
$ 319