GeneTex
United States (US)

TORC2 antibody

GTX31879_1522_IHC-P_20180221_18121410_560.jpg
GTX31879_1521_IHC-P_20180221_18121410_458.jpg
GTX31879_3026_WB_20180221_18121410_901.jpg

Cat No. GTX31879

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human, Mouse, Rat
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 - 2 μg/mL
IHC-P Assay dependent
ELISA Assay dependent
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

Positive Control

Human Small Intestine Tissue Lysate(GTX27923) , Human Small Intestine Tissue Slide

Specificity/Sensitivity

Multiple isoforms are known to exist.This antibody is predicted to not cross-react with CRTC1.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TORC2 antibody was raised against a 16 amino acid peptide near the carboxy terminus of human TORC2 .The immunogen is located within the last 50 amino acids of TORC2 .

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Creb Regulated Transcription Coactivator 2,Torc-2,Torc2,Crtc2

Background

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES
GTX31879_1522_IHC-P_20180221_18121410_560.jpg

GTX31879 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31879 TORC2 antibody.
Working concentration : 20 μg/ml

GTX31879_1521_IHC-P_20180221_18121410_458.jpg

GTX31879 IHC-P Image

IHC-P analysis of human small intestine tissue using GTX31879 TORC2 antibody.
Working concentration : 2.5 μg/ml

GTX31879_3026_WB_20180221_18121410_901.jpg

GTX31879 WB Image

WB analysis of human small intestine tissue lysate using GTX31879 TORC2 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Package List Price ($)
$ 329