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TORC2 (phospho Ser171) antibody

Orthogonal
Anti-TORC2 (phospho Ser171) antibody used in Western Blot (WB). GTX51565
Anti-TORC2 (phospho Ser171) antibody used in IHC (Paraffin sections) (IHC-P). GTX51565
Anti-TORC2 (phospho Ser171) antibody used in Western Blot (WB). GTX51565

Cat. No. GTX51565

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TORC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:300-1000
IHC-P 1:50-400
Not tested in other applications.

Calculated MW

73 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

1% BSA, 50% Glycerol

Preservative

0.09% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH conjugated synthetic phosphopeptide derived from human TORC2 around the phosphorylation site of Ser171

Purification

Protein A purified

Conjugation

Unconjugated

RRID

AB_2887781

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

CREB regulated transcription coactivator 2 , TORC-2 , TORC2

Cellular Localization

Cytoplasm,Nucleus

Background

This gene encodes a member of the transducers of regulated cAMP response element-binding protein activity family of transcription coactivators. These proteins promote the transcription of genes targeted by the cAMP response element-binding protein, and therefore play an important role in many cellular processes. Under basal conditions the encoded protein is phosphorylated by AMP-activated protein kinase or the salt-inducible kinases and is sequestered in the cytoplasm. Upon activation by elevated cAMP or calcium, the encoded protein translocates to the nucleus and increases target gene expression. Single nucleotide polymorphisms in this gene may increase the risk of type 2 diabetes. A pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES

Anti-TORC2 (phospho Ser171) antibody used in Western Blot (WB). GTX51565

GTX51565 WB Image

WB analysis of various samples using GTX51565 TORC2 (phospho Ser171) antibody.
Dilution : 1:200
Lane 1 : human rectal carcinoma lysates
Lane 2 : human gastric carcinoma lysates

Anti-TORC2 (phospho Ser171) antibody used in IHC (Paraffin sections) (IHC-P). GTX51565

GTX51565 IHC-P Image

IHC-P analysis of rat lung tissue using GTX51565 TORC2 (phospho Ser171) antibody.
Dilution : 1:200

Anti-TORC2 (phospho Ser171) antibody used in Western Blot (WB). GTX51565

GTX51565 WB Image

Orthogonal

The data was published in the journal Int J Mol Sci in 2019. PMID: 31540136

REFERENCE

Application Reference

Lee MY et al. Int J Mol Sci 2019; 20 (18) Liraglutide Inhibits Hepatitis C Virus Replication Through an AMP Activated Protein Kinase Dependent Mechanism.
Application : WB
Reactivity : Human
Submit a Reference

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399