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TRADD antibody

Anti-TRADD antibody used in Western Blot (WB). GTX66633
Anti-TRADD antibody used in IHC (Paraffin sections) (IHC-P). GTX66633

Cat. No. GTX66633

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse, Rat
Package
100 μl ($399)
See all TRADD products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
IHC-P 1:50-1:200
Not tested in other applications.

Calculated MW

34 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

15mM Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Synthetic peptide, corresponding to amino acids 250-304 of Human TRADD.

Purification

Purified by antigen-affinity chromatography
From serum

Purity

> 95% (by SDS-PAGE)

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

TNFRSF1A associated via death domain , Hs.89862

Cellular Localization

Nucleus,Cytoplasm,Cytoplasm, cytoskeleton

Background

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TRADD antibody used in Western Blot (WB). GTX66633

GTX66633 WB Image

WB analysis of various samples using GTX66633 TRADD antibody.
Lane1 : PC12 whole cell lysate(20ug)
Lane2 : AML-12 whole cell lysate(20ug)
Lane3 : MCF-7 whole cell lysate(40ug)
Lane4 : HEK293T whole cell lysate(40ug)
Lane5 : U-87MG whole cell lysate(40ug)
Lane6 : HepG2 whole cell lysate(40ug)
Lane7 : Hela whole cell lysate(40ug)
Dilution : 1:500

Anti-TRADD antibody used in IHC (Paraffin sections) (IHC-P). GTX66633

GTX66633 IHC-P Image

IHC-P analysis of human breast carcinoma tissue using GTX66633 TRADD antibody.
Dilution : 1:100

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399