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TRAF2 antibody, C-term

Anti-TRAF2 antibody, C-term used in Western Blot (WB). GTX89120
Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120
Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120
Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120

Cat No. GTX89120

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P
Reactivity Human
Package
100 μg ($329)
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.1-0.3μg/ml
IHC-P 3.75μg/ml

Note :

IHC-P
Human Kidney shows cytoplasm and select nuclear staining.

Not tested in other applications.

Calculated MW

56 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX89120-PEP).

Predict Reactivity

Mouse, Rat, Bovine, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.50 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide with sequence C-KMEAKNSYVRDD, from the C Terminus of the protein sequence according to NP_066961.2.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Tnf Receptor Associated Factor 2,Mgc:45012,Rnf117,Trap,Trap3,Traf2

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript varia

Database

Research Area

DATA IMAGES
Anti-TRAF2 antibody, C-term used in Western Blot (WB). GTX89120

GTX89120 WB Image

WB analysis of human ovary lysate using GTX89120 TRAF2 antibody, C-term.
Dilution : 0.1µg/ml
Loading : 35µg protein in RIPA buffer

Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120

GTX89120 IHC-P Image

IHC-P analysis of human kidney using GTX89120 TRAF2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.8µg/ml

Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120

GTX89120 IHC-P Image

IHC-P analysis of human pancreas using GTX89120 TRAF2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml

Anti-TRAF2 antibody, C-term used in IHC (Paraffin sections) (IHC-P). GTX89120

GTX89120 IHC-P Image

IHC-P analysis of human placenta using GTX89120 TRAF2 antibody, C-term.
Antigen retrieval : citrate buffer pH 6
Dilution : 3.75µg/ml

REFERENCE
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REVIEW
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Package List Price ($)
$ 329