GeneTex
United States (US)

TRAF3 antibody

GTX64473_20180530_ICCIF_18121411_189.jpg
GTX64473_20180530_WB_18121411_927.jpg

Cat No. GTX64473

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF
Reactivity Human, Mouse
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:200 - 1:1000
ICC/IF 1:50 - 1:200
Not tested in other applications.

Calculated MW

64 kDa. ( Note )
PROPERTIES

Form

Liquid

Buffer

PBS pH7.3, 0.02% sodium azide, 50% glycerol.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Antigen Species

Human

Immunogen

A synthetic peptide of human TRAF3

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

LAP1 Antibody , IIAE5 Antibody , CAP1 Antibody , CD40BP Antibody , CRAF1 Antibody

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. Several alternatively spliced transcript variants encoding three distinct isoforms have been reported. [provided by RefSeq, Dec 2010]

Database

Research Area

DATA IMAGES
GTX64473_20180530_ICCIF_18121411_189.jpg

GTX64473 ICC/IF Image

ICC/IF analysis of HeLa cell using GTX64473 TRAF3 antibody.
Blue : DAPI

GTX64473_20180530_WB_18121411_927.jpg

GTX64473 WB Image

WB analysis of various samples using GTX64473 TRAF3 antibody.
Dilution : 1:400
Loading : 25μg per lane

Package List Price ($)
$ 319