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TRAIL antibody

Anti-TRAIL antibody used in IHC (Paraffin sections) (IHC-P). GTX74230
Anti-TRAIL antibody used in Western Blot (WB). GTX74230

Cat No. GTX74230

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1-5 μg/mL
IHC-P 20μg/mL
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Predict Reactivity

Mouse(>80% identity)

PROPERTIES

Form

Liquid

Buffer

PBS, 0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TRAIL antibody was raised against a peptide corresponding to 17 amino acids near the carboxy terminus of human TRAIL. The immunogen is located within the last 50 amino acids of Trail.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Tnf Superfamily Member 10 , Apo2L , Apo-2L , Cd253 , Tl2 , Tnlg6A , Trail , Tnfsf10

Background

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Database

Research Area

DATA IMAGES

Anti-TRAIL antibody used in IHC (Paraffin sections) (IHC-P). GTX74230

GTX74230 IHC-P Image

IHC-P analysis of human brain tissue using GTX74230 TRAIL antibody.
Dilution : 20μg/ml

Anti-TRAIL antibody used in Western Blot (WB). GTX74230

GTX74230 WB Image

WB analysis of human brain tissue lysate using GTX74230 TRAIL antibody.
Lane A : 2.5μg/ml
Lane B : 5μg/ml

REFERENCE

There are currently no references for TRAIL antibody (GTX74230). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TRAIL antibody (GTX74230). Be the first to share your experience with this product.
SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339