GeneTex
  • Country / Location Selection

United States (US)

TREM2 antibody [HL1738]

Anti-TREM2 antibody [HL1738] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX637386
Anti-TREM2 antibody [HL1738] used in Western Blot (WB). GTX637386
Anti-TREM2 antibody [HL1738] used in Western Blot (WB). GTX637386
Anti-TREM2 antibody [HL1738] used in IHC (Paraffin sections) (IHC-P). GTX637386

Cat No. GTX637386

Host

Rabbit

Clonality

Monoclonal

Clone Name

HL1738

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human
Package
100 μl ($379),
25 μl ($169)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

25 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

No Preservative

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

full length human TREM2 recombinant protein.

Purification

Affinity purified by Protein A.

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

triggering receptor expressed on myeloid cells 2 , PLOSL2 , TREM-2 , Trem2a , Trem2b , Trem2c

Background

This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2012]

Database

Research Area

DATA IMAGES

Anti-TREM2 antibody [HL1738] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX637386

GTX637386 ICC/IF Image

TREM2 antibody [HL1738] detects TREM2 protein at cell membrane and cytoplasm by immunofluorescent analysis.
Sample: THP-1 cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: TREM2 stained by TREM2 antibody [HL1738] (GTX637386) diluted at 1:250.
Blue: Fluoroshield with DAPI (GTX30920).

Anti-TREM2 antibody [HL1738] used in Western Blot (WB). GTX637386

GTX637386 WB Image

Various whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TREM2 antibody [HL1738] (GTX637386) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody, and the signal was developed with Trident ECL plus-Enhanced. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.

Anti-TREM2 antibody [HL1738] used in Western Blot (WB). GTX637386

GTX637386 WB Image

Non-transfected (–) and transfected (+) 293T whole cell extracts (30 μg) were separated by 12% SDS-PAGE, and the membrane was blotted with TREM2 antibody [HL1738] (GTX637386) diluted at 1:500. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Anti-TREM2 antibody [HL1738] used in IHC (Paraffin sections) (IHC-P). GTX637386

GTX637386 IHC-P Image

TREM2 antibody [HL1738] detects TREM2 protein at cell membrane by immunohistochemical analysis.
Sample: Paraffin-embedded human lung cancer.
TREM2 stained by TREM2 antibody [HL1738] (GTX637386) diluted at 1:200.
Antigen Retrieval: Citrate buffer, pH 6.0, 15 min

REFERENCE

There are currently no references for TREM2 antibody [HL1738] (GTX637386). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TREM2 antibody [HL1738] (GTX637386). Be the first to share your experience with this product.
Package List Price ($)
$ 379
$ 169
Custom Conjugations