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TREX1 antibody

Anti-TREX1 antibody used in Western Blot (WB). GTX31367
Anti-TREX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31367
Anti-TREX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31367

Cat No. GTX31367

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, IHC-P, ELISA

Reactivity

Human, Mouse, Rat
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5 - 1 μg/mL
IHC-P 2.5 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

33 kDa. ( Note )

Positive Control

Human Spleen Tissue Lysate(GTX27921) , Human Spleen Tissue Slide

Specificity/Sensitivity

TREX1 antibody will not cross-react with the related protein TREX2. At least three isoforms of TREX1 are known to exist; this antibody will recognize all three isoforms.

PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TREX1 antibody was raised against a 15 amino acid synthetic peptide near the center of human TREX1.The immunogen is located within amino acids 220 - 270 of TREX1.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

three prime repair exonuclease 1 , AGS1 , CRV , DRN3 , HERNS

Cellular Localization

Nucleus,Cytoplasm, cytosol

Background

This gene encodes a nuclear protein with 3' exonuclease activity. The encoded protein may play a role in DNA repair and serve as a proofreading function for DNA polymerase. Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, Cree encephalitis, and other diseases of the immune system. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012]

Database

Research Area

DATA IMAGES

Anti-TREX1 antibody used in Western Blot (WB). GTX31367

GTX31367 WB Image

WB analysis of human spleen tissue lysate using GTX31367 TREX1 antibody.
Working concentration : (A) 0.5 and (B) 1 μg/ml

Anti-TREX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31367

GTX31367 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31367 TREX1 antibody.
Working concentration : 20 μg/ml

Anti-TREX1 antibody used in IHC (Paraffin sections) (IHC-P). GTX31367

GTX31367 IHC-P Image

IHC-P analysis of human spleen tissue using GTX31367 TREX1 antibody.
Working concentration : 2.5 μg/ml

REFERENCE

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REVIEW

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SDS
PBS.pdf
Sodium Azide.pdf
Package List Price ($)
$ 339