PBS + 0.1% sodium azide
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
hTRF1 AS, NIMA interacting protein 2, PIN2, t TRF1, TERF 1, TRBF 1, TRF 1, TTAGGG repeat binding factor 1, Telomeric protein Pin2/TRF1, Telomeric repeat binding factor (NIMA interacting) 1,
Colocalizes with telomeric DNA in interphase and metaphase cells and is located at chromosome ends during metaphase. Associates with the mitotic spindle.
The TRF1 gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. It is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.