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TRF1 antibody

Anti-TRF1 antibody used in Western Blot (WB). GTX32935

Cat. No. GTX32935

Reference 1

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, PLA

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all TRF1 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:2000
PLA Assay dependent
Not tested in other applications.

Calculated MW

50 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 50% Glycerol

Preservative

0.02% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 240-419 of human TERF1 (NP_003209.2).

Purification

Purified by affinity chromatography

Conjugation

Unconjugated

RRID

AB_2887688

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

telomeric repeat binding factor 1 , PIN2 , TRBF1 , TRF , TRF1 , hTRF1-AS , t-TRF1

Cellular Localization

Nucleus

Background

This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TRF1 antibody used in Western Blot (WB). GTX32935

GTX32935 WB Image

WB analysis of various sample lysates using GTX32935 TRF1 antibody.
Dilution : 1:1000
Loading : 25μg per lane

REFERENCE

Application Reference

Bottoni G et al. Nat Commun 2019; 10 (1) : 3884 CSL controls telomere maintenance and genome stability in human dermal fibroblasts.
Application : WB, PLA
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REVIEW

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SDS
PBS.pdf
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399