GeneTex
United States (US)

TRIM37 antibody [C3], C-term

GTX106280_40905_WB_19011506_653.jpg
GTX106280_40905_IHC_19011506_776.jpg
GTX106280_40905_20150525_IFA_19011506_749.jpg

Cat No. GTX106280

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, ICC/IF, IHC-P
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500-1:3000
ICC/IF 1:100-1:1000
IHC-P 1:100-1:1000
Not tested in other applications.

Calculated MW

108 kDa. ( Note )

Positive Control

A431 , HeLa , HepG2

Predict Reactivity

Bovine, Rhesus Monkey(>80% identity)
PROPERTIES

Form

Liquid

Buffer

1XPBS, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

Concentration

1mg/ml

Antigen Species

Human

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human TRIM37. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography.

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

KIAA0898 antibody, MUL antibody, POB1 antibody, TEF3 antibody, TRIM37 antibody, tripartite motif-containing 37 antibody, E3 ubiquitin-protein ligase TRIM37 antibody, RING-B-box-coiled-coil protein antibody, mulibrey nanism protein antibody, tripartite motif-containing protein 37 antibody, tripartite motif containing 37 antibody

Cellular Localization

Cytoplasm , Peroxisome

Background

This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellular functions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RING finger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might be involved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq]
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Database

DATA IMAGES
GTX106280_40905_WB_19011506_653.jpg

GTX106280 WB Image

Sample (30 ug of whole cell lysate)
A: A431
B: HeLa
C: HepG2
7.5% SDS PAGE
GTX106280 diluted at 1:1000

GTX106280_40905_IHC_19011506_776.jpg

GTX106280 IHC-P Image

Immunohistochemical analysis of paraffin-embedded U87 xenograft, using TRIM37(GTX106280) antibody at 1:500 dilution.
Antigen Retrieval: Trilogy™ (EDTA based, pH 8.0) buffer, 15min

GTX106280_40905_20150525_IFA_19011506_749.jpg

GTX106280 ICC/IF Image

TRIM37 antibody [C3], C-term detects TRIM37 protein at cytoplasm and nucleus by immunofluorescent analysis.
Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.
Green: TRIM37 protein stained by TRIM37 antibody [C3], C-term (GTX106280) diluted at 1:500.
Blue: Hoechst 33342 staining.
Scale bar = 10 μm.

SDS
PBS.pdf
Glycerol.pdf
Thimerosal.pdf
Package List Price ($)
$ 319
$ 169