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United States (US)

TRIM5 blocking peptide

Cat No. GTX47603-PEP

Species

Human
Package
100 μg ($239)

APPLICATION

Specificity/Sensitivity

The peptide was used in the production of GTX47603.

PROPERTIES

Form

Lyophilized powder

Buffer

Lyophilized from 5% (v/v) acetonitrile/H₂O. Reconstitute pellet in 200μl distilled water to obtain a 0.5mg/ml peptide solution.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Region/Sequence

ASGILVNVKEEVTC

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Tripartite Motif Containing 5 , Rnf88 , Trim5Alpha , Trim5

Background

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein forms homo-oligomers via the coilel-coil region and localizes to cytoplasmic bodies. It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization. It may play a role in retroviral restriction. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2009]

Research Area

REFERENCE

There are currently no references for TRIM5 blocking peptide (GTX47603-PEP). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TRIM5 blocking peptide (GTX47603-PEP). Be the first to share your experience with this product.