GeneTex
  • Country / Location Selection

United States (US)

TRIP230 antibody [10G5]

Anti-TRIP230 antibody [10G5] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70253

Cat No. GTX70253

Host

Mouse

Clonality

Monoclonal

Clone Name

10G5

Isotype

IgG1

Application

WB, ICC/IF, IP

Reactivity

Human
Package
100 μl ($329)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:500
ICC/IF Assay dependent
IP Assay dependent
Not tested in other applications.

Calculated MW

228 kDa. ( Note )

Positive Control

MCF7, HBL100, T24

PROPERTIES

Form

Liquid

Buffer

Phosphate-buffered saline, pH 7.4, containing no preservatives

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Amino acids 1099-1372 of Trip230 expressed in E. coli.

Purification

Protein G purified
From tissue culture supernatant

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

Thyroid Hormone Receptor Interactor 11 , Acg1A , Cev14 , Gmap-210 , Gmap210 , Trip-11 , Trip230 , Trip11

Background

The Trip230 gene encodes a protein of 1,978 amino acids with an estimated molecular mass of 230 kDa. The gene is located on chromosome 14q31, which is in a region associated with genetic alterations and thyroid hormone response abnormalities. The Trip230 protein interacts with Rb and thyroid hormone receptor (TR) using two distinct domains. Complex formation with Rb is in a hormone independent manner, but when Trip230 forms a complex with TR, it is in a thyroid hormone-dependent manner. After T3 treatment, Trip230 is phosphorylated and transported to the nucleus, suggesting that phosphorylation may be important for its nuclear translocation.

Database

Research Area

DATA IMAGES

Anti-TRIP230 antibody [10G5] used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX70253

GTX70253 ICC/IF Image

Immunofluorescence analysis of methanol-fixed HeLa, using TRIP230(GTX70253) antibody at 1:100 dilution.

REFERENCE

There are currently no references for TRIP230 antibody [10G5] (GTX70253). Be the first to share your publications with this product.

REVIEW

There are currently no reviews for TRIP230 antibody [10G5] (GTX70253). Be the first to share your experience with this product.