*Optimal dilutions/concentrations should be determined by the researcher.
Not tested in other applications.
K-562 Cell Slide(GTX25535) , K562 Cell Lysate(GTX27911)
This antibody is predicted to not cross-react with other TYW protein family members. At least two isoforms are known to exist; this antibody will detect both isoforms
PBS with 0.02% sodium azide.
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
1 mg/ml (Please refer to the vial label for the specific concentration.)
TRMT12 antibody was raised against a 19 amino acid synthetic peptide near the amino terminus of human TRMT12.The immunogen is located within the first 50 amino acids of TRMT12.
Purified by antigen-affinity chromatography
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
tRNA methyltransferase 12 homolog , TRM12 , TYW2
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]