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TRPM2 antibody

Anti-TRPM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04802
Anti-TRPM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04802

Cat. No. GTX04802

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, ICC/IF, IHC-P, IHC-Fr

Reactivity

 Mouse, Rat
Package
100 μl ($429)
See all TRPM2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500-1:1000
ICC/IF 1:10-1:500
IHC-P 1:200
IHC-Fr 1:200
Not tested in other applications.

Calculated MW

172 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS

Preservative

0.02% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

A synthetic peptide made to a C-terminal portion of the rat TRPM2 protein (Swiss-Prot# Q5G856),within residues 1430-1508.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel, subfamily M, member 2 , Trpm2-predicted

Cellular Localization

Cell membrane , Cytoplasmic vesicle , Lysosome

Background

Predicted to enable calcium ion binding activity; metal ion transmembrane transporter activity; and mono-ADP-D-ribose binding activity. Involved in several processes, including calcium ion import across plasma membrane; estrous cycle; and positive regulation of insulin secretion. Located in neuron projection; neuronal cell body; and plasma membrane. Biomarker of transient cerebral ischemia. Orthologous to human TRPM2 (transient receptor potential cation channel subfamily M member 2). [provided by Alliance of Genome Resources, Apr 2022]

Database

Research Area

DATA IMAGES

Anti-TRPM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04802

GTX04802 ICC/IF Image

ICC/IF analysis of 4%PFA-fixed Neuro2a cells using GTX04802 TRPM2 antibody.
Green : Primary antibody
Blue : DAPI
Permeabilization : 0.05% Triton X-100
Dilution : 5 μg/ml

Anti-TRPM2 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX04802

GTX04802 ICC/IF Image

ICC/IF analysis of Neuro2a cells using GTX04802 TRPM2 antibody.
Green : Primary antibody
Red : alpha-tubulin
Blue : DAPI

REFERENCE

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REVIEW

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Package List Price ($)
$ 429