GeneTex
United States (US)

TRPM7 antibody

Cat No. GTX16576

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IP
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1:1000
IP 5 ul
Not tested in other applications.

Calculated MW

213 kDa. ( Note )

Specificity/Sensitivity

This product does not react with Mouse,Rat.
PROPERTIES

Form

Liquid

Buffer

Serum, 0.05% Sodium Azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Rat

Immunogen

A synthetic peptide made to the C-terminal region of rat TRPM7. [UniProt# Q925B3]

Purification

Unpurified

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transient Receptor Potential Cation Channel Subfamily M Member 7,Alspdc,Chak,Chak1,Ltrpc7,Ltrpc-7,Trp-Plik,Trpm7

Cellular Localization

Membrane, Multi-pass membrane protein

Background

TRPCs, mammalian homologs of the Drosophila transient receptor potential (trp) protein, are ion channels that are thought to mediate capacitative calcium entry into the cell. TRP-PLIK is a protein that is both an ion channel and a kinase. As a channel, it conducts calcium and monovalent cations to depolarize cells and increase intracellular calcium. As a kinase, it is capable of phosphorylating itself and other substrates. The kinase activity is necessary for channel function, as shown by its dependence on intracellular ATP and by the kinase mutants.[supplied by OMIM]

Database

Research Area

Package List Price ($)
$ 319