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TRPM7 antibody

Anti-TRPM7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54865
Anti-TRPM7 antibody used in Western Blot (WB). GTX54865
Anti-TRPM7 antibody used in IHC (Paraffin sections) (IHC-P). GTX54865

Cat No. GTX54865

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

WB, ICC/IF, IHC-P

Reactivity

Human, Mouse, Rat
Package
50 μl ($389)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB Assay dependent
ICC/IF Assay dependent
IHC-P Assay dependent
Not tested in other applications.

Calculated MW

213 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS pH 7.4, 1% BSA, 0.05% sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.8 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide CKRRKKDKTSDGPKLFLTEE, corresponding to amino acid residues 1146-1165 (Intracellular, C-terminus) of human TRPM7 (Accession  : Q96QT4).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

transient receptor potential cation channel subfamily M member 7 , ALSPDC , CHAK , CHAK1 , LTRPC7 , LTrpC-7 , TRP-PLIK

Cellular Localization

Membrane

Background

This gene belongs to the melastatin subfamily of transient receptor potential family of ion channels. The protein encoded by this gene is both an ion channel and a serine/threonine protein kinase. The kinase activity is essential for the ion channel function, which serves to increase intracellular calcium levels and to help regulate magnesium ion homeostasis. The encoded protein is involved in cytoskeletal organization, cell adhesion, cell migration and organogenesis. Defects in this gene are a cause of amyotrophic lateral sclerosis-parkinsonism/dementia complex of Guam. The gene may also be associated with defects of cardiac function. [provided by RefSeq, Aug 2017]

Database

Research Area

DATA IMAGES

Anti-TRPM7 antibody used in Immunocytochemistry/ Immunofluorescence (ICC/IF). GTX54865

GTX54865 ICC/IF Image

ICC/IF analysis of GH3 cells using GTX54865 TRPM7 antibody.
Panel A : Primary antibody
Panel B : DNA dye Hoechst 33342
Panel C : Live intact GH3 cells
Dilution : 1:100

Anti-TRPM7 antibody used in Western Blot (WB). GTX54865

GTX54865 WB Image

WB analysis of GH3 cell line (lanes 1 and 2) and mouse brain (lanes 3 and 4) lysates using GTX54865 TRPM7 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

Anti-TRPM7 antibody used in IHC (Paraffin sections) (IHC-P). GTX54865

GTX54865 IHC-P Image

IHC-P analysis of rat pituitary gland tissue using GTX54865 TRPM7 antibody. Hematoxilin is used as the Counterstain.
Dilution : 1:50

REFERENCE

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REVIEW

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Package List Price ($)
$ 389