GeneTex
United States (US)

TRPV3 antibody, Internal

GTX88648_2667_WB_18121411_337.jpg

Cat No. GTX88648

Host Goat
Clonality Polyclonal
Isotype IgG
Application WB
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 0.5-1μg/ml
Not tested in other applications.

Calculated MW

91 kDa. ( Note )

Positive Control

The peptide used to generate this antibody is available for purchase (GTX88648-PEP).

Predict Reactivity

Mouse, Rat, Dog(>80% identity)
PROPERTIES

Form

Liquid

Buffer

Tris saline pH7.3, 0.02% sodium azide, 0.5% BSA.

Concentration

0.50mg/ml

Antigen Species

Human

Immunogen

Peptide with sequence C-NKIQDSSRNNSK, from the internal region (near C Terminus) of the protein sequence according to NP_659505.1.

Purification

Purified by ammonium sulphate precipitation followed by antigen affinity chromatography

Conjugation

Unconjugated

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

VRL3 Antibody , OLMS Antibody

Background

This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
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Database

Research Area

DATA IMAGES
GTX88648_2667_WB_18121411_337.jpg

GTX88648 WB Image

WB analysis of HEK293 overexpressing human TRPV3 with DYKDDDDK tag using GTX88648 TRPV3 antibody, Internal.
Lane A : primary antibody
Lane B : Mock-transfected HEK293 probed with primary antibody
Lane C : Tag antibody
Dilution : 0.5µg/ml
Loading : 10µg protein in RIPA buffer