TRPV3 antibody

Cat. No. GTX54763

Host	Rabbit
Clonality	Polyclonal
Isotype	IgG
Application	WB, ICC/IF, IHC-Fr, LCI
Reactivity	Human, Mouse, Rat
Package	50 μl ($639)

See all TRPV3 products

Datasheet
Document

View product citations for antibody GTX54763 on CiteAb

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.

Application	Recommended Dilution
WB	Assay dependent
ICC/IF	Assay dependent
IHC-Fr	Assay dependent
LCI	Assay dependent

Not tested in other applications.

Calculated MW

91 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS, 1% BSA

Preservative

0.05% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

0.85 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

Peptide (C)REEEAIPHPLALTHK, corresponding to amino acid residues 464-478 (1st extracellular loop) of human TRPV3 (Accession : Q8NET8).

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

transient receptor potential cation channel subfamily V member 3 , FNEPPK2 , OLMS , VRL3

Cellular Localization

Membrane; Multi-pass membrane protein

Background

This gene product belongs to a family of nonselective cation channels that function in a variety of processes, including temperature sensation and vasoregulation. The thermosensitive members of this family are expressed in subsets of sensory neurons that terminate in the skin, and are activated at distinct physiological temperatures. This channel is activated at temperatures between 22 and 40 degrees C. This gene lies in close proximity to another family member gene on chromosome 17, and the two encoded proteins are thought to associate with each other to form heteromeric channels. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Database

Gene ID: 162514 TRPV3
UniProt: Q8NET8 TRPV3

Research Area

DATA IMAGES

GTX54763 IHC-Fr Image

IHC-Fr analysis of mouse spinal cord tissue using GTX54763 TRPV3 antibody. The inset in panel C magnifies one large motor neuron (vertical arrowhead). Note the punctate pattern of TRPV3 on the surface of the soma.
Panel A : TRPV3 (green) appears in neurons (vertical arrows) in the ventral horn of the mouse spinal cord.
Panel B : Motor neurons were stained with goat anti-choline-acetyltransferase (red). In some motor neurons (A) TRPV3 was more intense (vertical arrow) whereas in others it was weak (horizontal arrows).
Panel C : Merged images of panels A and B.

GTX54763 LCI Image

Live cell imaging analysis of living rat dorsal root ganglion (DRG) using GTX54763 TRPV3 antibody.
Panel A : Primary antibody (Orange)
Panel B : Hoechst 33342 for nuclear staining (blue)
Panel C : Merged images of Panel A and B
Dilution : 1:50-1:100

GTX54763 WB Image

WB analysis of rat DRG (lanes 1 and 2) and brain (lanes 3 and 4) lysates using GTX54763 TRPV3 antibody preincubated with or without immunogen peptide.
Dilution : 1:200

REFERENCE

There are currently no references for TRPV3 antibody (GTX54763). Be the first to share your publications with this product.

Submit a Reference

REVIEW

There are currently no reviews for TRPV3 antibody (GTX54763). Be the first to share your experience with this product.

Submit a Review

SDS
PBS.pdf
Sodium Azide.pdf

Package

List Price ($)

50 μl

$ 639

Qty