GeneTex
United States (US)

TRPV4 antibody

Anti-TRPV4 antibody used in Western Blot (WB). GTX31567
Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567
Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567
Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567
Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567

Cat No. GTX31567

Host Rabbit
Clonality Polyclonal
Isotype IgG
Application WB, IHC-P, ELISA
Reactivity Human
APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
WB 1 μg/mL
IHC-P 2 μg/mL
ELISA Assay dependent
Not tested in other applications.

Calculated MW

98 kDa. ( Note )

Positive Control

SK-N-SH Cell Lysate(GTX23956) , Human Lung Tissue Slide

Specificity/Sensitivity

TRPV4 antibody is human specific. At least six isoforms of TRPV4 are known to exist. This antibody is predicted to not cross-react with other TRP protein family members.
PROPERTIES

Form

Liquid

Buffer

PBS with 0.02% sodium azide.

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

1 mg/ml (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

TRPV4 antibody was raised against an 18 amino acid peptide near the center of human TRPV4.The immunogen is located within amino acids 380 - 430 of TRPV4.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
TARGET

Synonyms

Transient Receptor Potential Cation Channel Subfamily V Member 4,Bcym3,Cmt2C,Hmsn2C,Otrpc4,Smal,Spsma,Ssqtl1,Trp12,Vrl2,Vroac,Trpv4

Background

This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Database

Research Area

DATA IMAGES
Anti-TRPV4 antibody used in Western Blot (WB). GTX31567

GTX31567 WB Image

WB analysis of (A) human testis tissue and (B) SK-N-SH cell lysate using GTX31567 TRPV4 antibody.
Working concentration : 1 μg/ml

Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567

GTX31567 IHC-P Image

IHC-P analysis of human lung tissue using GTX31567 TRPV4 antibody.
Working concentration : 20 μg/ml

Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567

GTX31567 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31567 TRPV4 antibody.
Working concentration : 5 μg/ml

Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567

GTX31567 IHC-P Image

IHC-P analysis of human kidney tissue using GTX31567 TRPV4 antibody.
Working concentration : 2 μg/ml

Anti-TRPV4 antibody used in IHC (Paraffin sections) (IHC-P). GTX31567

GTX31567 IHC-P Image

IHC-P analysis of human lung tissue using GTX31567 TRPV4 antibody.
Working concentration : 5 μg/ml

Package List Price ($)
$ 329