APPLICATION
Application Note
*Optimal dilutions/concentrations should be determined by the researcher.
| Application |
Recommended Dilution |
| 1 μg/mL |
| 2 μg/mL |
| Assay dependent |
Not tested in other applications.
Calculated MW
Positive Control
SK-N-SH Cell Lysate(GTX23956) , Human Lung Tissue Slide
Product Note
TRPV4 antibody is human specific. At least six isoforms of TRPV4 are known to exist. This antibody is predicted to not cross-react with other TRP protein family members.
PROPERTIES
Form
Liquid
Buffer
PBS
Preservative
0.02% Sodium azide
Storage
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Concentration
1 mg/ml (Please refer to the vial label for the specific concentration.)
Antigen Species
Human
Immunogen
TRPV4 antibody was raised against an 18 amino acid peptide near the center of human TRPV4.The immunogen is located within amino acids 380 - 430 of TRPV4.
Purification
Purified by antigen-affinity chromatography
Conjugation
Unconjugated
Note
For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.
TARGET
Synonyms
transient receptor potential cation channel subfamily V member 4 , BCYM3 , CMT2C , HMSN2C , OTRPC4 , SMAL , SPSMA , SSQTL1 , TRP12 , VRL2 , VROAC
Cellular Localization
Apical cell membrane
Background
This gene encodes a member of the OSM9-like transient receptor potential channel (OTRPC) subfamily in the transient receptor potential (TRP) superfamily of ion channels. The encoded protein is a Ca2+-permeable, nonselective cation channel that is thought to be involved in the regulation of systemic osmotic pressure. Mutations in this gene are the cause of spondylometaphyseal and metatropic dysplasia and hereditary motor and sensory neuropathy type IIC. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]
Database
Research Area
DATA IMAGES
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GTX31567 IHC-P Image
IHC-P analysis of human kidney tissue using GTX31567 TRPV4 antibody.
Working concentration : 2 μg/ml
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GTX31567 IHC-P Image
IHC-P analysis of human lung tissue using GTX31567 TRPV4 antibody.
Working concentration : 20 μg/ml
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GTX31567 WB Image
WB analysis of (A) human testis tissue and (B) SK-N-SH cell lysate using GTX31567 TRPV4 antibody.
Working concentration : 1 μg/ml
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GTX31567 IHC-P Image
IHC-P analysis of human kidney tissue using GTX31567 TRPV4 antibody.
Working concentration : 5 μg/ml
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GTX31567 IHC-P Image
IHC-P analysis of human lung tissue using GTX31567 TRPV4 antibody.
Working concentration : 5 μg/ml
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REFERENCE
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REVIEW
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