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TSC2 (phospho Ser1254) antibody

Anti-TSC2 (phospho Ser1254) antibody used in IHC (Paraffin sections) (IHC-P). GTX78927

Cat No. GTX78927

Host

Rabbit

Clonality

Polyclonal

Isotype

IgG

Application

IHC-P

Reactivity

Human
Package
100 μg ($339)

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Dilution
IHC-P 1:50 - 1:100
Not tested in other applications.

Calculated MW

201 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

PBS (without Mg²⁺ and Ca²⁺) pH 7.4, 150mM NaCl, 0.02% sodium azide, 50% glycerol

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

The antiserum was produced against synthesized phosphopeptide derived from human Tsc2 around the phosphorylation site of serine 1254 (S-L-Sp-V-P).

Purification

Purified by sequential chromatography on phospho- and non-phospho-peptide affinity columns.
From serum

Conjugation

Unconjugated

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

TARGET

Synonyms

LAM,PPP1R160,TSC2,TSC4,tuberous sclerosis 2,Tuberin,TSC complex subunit 2

Cellular Localization

Cytoplasm,Membrane

Background

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TSC2 (phospho Ser1254) antibody used in IHC (Paraffin sections) (IHC-P). GTX78927

GTX78927 IHC-P Image

IHC-P analysis of human prostate carcinoma tissue using GTX78927 TSC2 (phospho Ser1254) antibody.

REFERENCE

There are currently no references for TSC2 (phospho Ser1254) antibody (GTX78927). Be the first to share your publications with this product.

REVIEW

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Package List Price ($)
$ 339