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TSC2 (phospho Ser939) antibody

Anti-TSC2 (phospho Ser939) antibody used in Western Blot (WB). GTX54996
Anti-TSC2 (phospho Ser939) antibody used in IHC (Paraffin sections) (IHC-P). GTX54996

Cat. No. GTX54996

Host

 Rabbit

Clonality

 Polyclonal

Isotype

 IgG

Application

 WB, IHC-P

Reactivity

 Human, Mouse
Package
100 μl ($399)
See all TSC2 products

APPLICATION

Application Note

*Optimal dilutions/concentrations should be determined by the researcher.
Application Recommended Dilution
WB 1:500 - 1:1000
IHC-P 1:100 - 1:200
Not tested in other applications.

Calculated MW

201 kDa. ( Note )

PROPERTIES

Form

Liquid

Buffer

0.42% Potassium Phosphate, 0.87% NaCl, 30% Glycerol

Preservative

0.01% Sodium azide

Storage

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

Concentration

Batch dependent (Please refer to the vial label for the specific concentration.)

Antigen Species

Human

Immunogen

KLH-conjugated synthetic peptide encompassing a sequence within the center region of TSC2. The exact sequence is proprietary.

Purification

Purified by antigen-affinity chromatography

Conjugation

Unconjugated

Note

For laboratory research use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.

Purchasers shall not, and agree not to enable third parties to, analyze, copy, reverse engineer or otherwise attempt to determine the structure or sequence of the product.

TARGET

Synonyms

TSC complex subunit 2 , LAM , PPP1R160 , TSC4

Cellular Localization

Cytoplasm

Background

Mutations in this gene lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Database

Research Area

DATA IMAGES

Anti-TSC2 (phospho Ser939) antibody used in Western Blot (WB). GTX54996

GTX54996 WB Image

WB analysis of insulin-treated HEK293T (A), insulin-treated NIH3T3 (B) whole cell lysates using GTX54996 TSC2 (phospho Ser939) antibody.

Anti-TSC2 (phospho Ser939) antibody used in IHC (Paraffin sections) (IHC-P). GTX54996

GTX54996 IHC-P Image

IHC-P analysis of formalin fixed human breast cancer tissue section using GTX54996 TSC2 (phospho Ser939) antibody.
Antigen retrieval : Heat mediated antigen retrieval with sodium citrate buffer (pH 6.0)

REFERENCE

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REVIEW

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SDS
Glycerol.pdf
Sodium Azide.pdf
Package List Price ($)
$ 399